Modvate 3 Cream

Modvate 3 Cream (Beclometasone Dipropionate, Cotrimazole, Neomycin Sulphate) is prescribed to treat resistant dermatoses where secondary bacterial or fungal infection is present, suspected, or likely to occur.

Modvate 3

Beclometasone dipropionate/ Clotrimazole/ Neomycin sulphate

Modvate 3

10g

GSK

Cream

Beclometasone 0.025% / Clotrimazole 1% / Neomycin 0.5%

India

Out of Stock.

Modvate 3 Cream

I. Introduction to Modvate 3 Cream

Overview of Modvate 3 Cream

Motivate 3 Cream is a type of skin medication that helps with skin conditions that cause inflammation and irritation on the skin surface. It works by reducing inflammation and redness while also relieving itching, which is commonly seen in skin issues. It aims to target the causes of discomfort and irritation for effective relief.

Therapeutic Class and Active Ingredients

Modvate 3 Cream is classified as a strength corticosteroid medication that contains Clobetasol Propionate as the primary active ingredient known for its anti inflammatory and immunosuppressive properties. The cream also includes ingredients to help moisturize the skin and maintain the formulation’s stability.

Availability and Prescription Status

Modulate 3 Cream requires a prescription due to its components that need medical supervision for safe usage. You can purchase it at pharmacies; however its availability may differ depending on where you're the local rules governing corticosteroids.

II. Composition of Modvate 3 Cream

Detailed Breakdown of Active and Inactive Ingredients

- Active ingredient**: Clobetasol Propionate (0.05%)

- Inactive ingredients: Propylene glycol, cetostearyl alcohol, white soft paraffin, chlorocresol, purified water.



Role of Each Component in the Formulation

Clobetasol Propionate helps to reduce inflammation in the skin by limiting the production of substances that result in swelling and redness appearance on the surface of the skin. Propylene glycol aids in boosting the absorption of the ingredient, while cetostearyl alcohol contributes emulsifying characteristics to the formula. White soft paraffin functions, as a moisturizer to prevent dryness and chlorocresol acts as a preservative to prolong the shelf life of the cream.

Common Alternatives to Modvate 3 Cream’s Composition

Other options could involve trying out types of cortisone medications, like hydrocortisone or betamethasone, with varying potencies based on the seriousness of the ailment being addressed.

Clobetasone vs hydrocortisone

Clobetasol cream is more potent than steroid creams, like hydrocortisone 1%. Typically, individuals only require clobetasol application twice daily for a week, though a physician might recommend using it for a period exceeding one week.

Clobetasol and clobetasone

Clobetasol can only be obtained with a prescription. It is offered in forms like cream and shampoo for scalp treatment and ointment options available in the market. There is another product called clobetasone that resembles clobetasol but is gentler in comparison and can be purchased directly at pharmacies or stores.

Hydrocortisone vs clobetasone

Clobetasol cream is more potent than steroid creams, like 1%. Typically, individuals apply clobetasol twice daily for a week, though a physician might recommend a usage period exceeding one week.

Clobetasol propionate vs triamcinolone acetonide

The effectiveness of clobetasol propionate 0..05 % ointment is greater than that of triamcinolone acetonide 0..01 % ointment.

III. Uses of Modvate 3 Cream

Approved Medical Uses

Modvate 3 Cream is commonly used for the treatment of:

- Psoriasis

- Eczema

- Allergic contact dermatitis

- Seborrheic dermatitis

Treatment for Inflammatory Skin Conditions

Skin conditions characterized by redness and swelling often cause discomfort. Modvate 3 Cream is known for alleviating these symptoms and providing relief after application. ts strong formula is ideal for treating flare ups of conditions.


Application in Eczema and Psoriasis

The cream is beneficial for individuals with eczema as it provides relief to the skin and helps restore its protective barrier against external factors such as allergens or irritants. In cases of psoriasis, it alleviates the scaling and thickening of the skin caused by the turnover of cells in affected areas.

Management of Dermatitis and Allergic Reactions

When someone experiences a reaction like contact dermatitis, Modvate 3 Cream helps calm the system's reaction, causing the rash, resulting in less severe symptoms.

Relief of Itching, Redness, and Swelling

One of the cream's advantages is its relief of itching, which is a common symptom in many inflammatory conditions. Redness and swelling decrease shortly thereafter.

Off-label Uses of Modvate 3 Cream

Treatment of Acne

While not commonly prescribed for acne treatment purposes, Modvate 3 Cream has sometimes been utilized to alleviate inflammation associated with acne flare-ups, such as cystic acne outbreaks.


Use for Hyperpigmentation

In dermatology, when dealing with inflammatory hyperpigmentation issues on the skin surface area, doctors may recommend the use of Modavate 3 Cream to assist in reducing the appearance of darkened patches on the skin.

Use in Post-surgical Scar Management

The ointment is used on scars to help reduce inflammation and lower the chances of developing raised scars; however that is not its purpose.

Clobetasol propionate for vulvar itching and burning

Clobetasol Propionate 0.05 percent Gel is a cortisone medication created for treating skin and vaginal issues by reducing inflammation and alleviating itching effectively when used topically or vaginally.

Clobetasol propionate poison ivy

Clobetasone propionate could be applied to heal a poison ivy rash before it forms blisters or if the rash is limited to a section.

Clobetasol propionate for hair loss

Studies indicate that hair regrowth was triggered in 25 30 percent of individuals who applied clobetasol while around 50 percent experienced hair regrowth with the use of clobetasol cream.

IV. How Modvate 3 Cream Works

Mechanism of Action: How Corticosteroids Reduce Inflammation

Corticosteroids such as Clobetasol Propionate work by decreasing inflammation by blocking the release of inflammatory cytokines that trigger the body's inflammatory response. Modulate 3 Cream helps reduce swelling and redness in the area by inhibiting the action of these molecules.


Interaction with the Immune Response

Modulate Cream 3 has soothing properties that can also regulate the system response and provide relief for conditions such as eczema and psoriasis by preventing the system from attacking healthy skin cells erroneously.

Time to Symptom Relief After Application

Patients often start feeling better and notice a reduction in symptoms after using the treatment for a day. In cases of conditions such as psoriasis, longer treatment durations might be needed to sustain the outcomes.

V. Clobetasol propionate dosage

For adults experiencing skin issues, apply an amount of Modovate 3 Cream to the area once or twice a day as needed; it's important to use the treatment for the shortest duration possible to minimize any side effects that may occur.

Frequency of Application

For moderate to severe conditions, the usual practice is to use it daily. When symptoms get better, the doctor may suggest reducing the frequency to once a day or every other day.

Proper Method of Application

  1. Ensure that you clean and dry the area that has been impacted.
  2. Gently apply a layer by massaging it onto the skin.
  3. Refrain, from using much as it could heighten the chances of experiencing effects.

Duration of Treatment and Tapering Recommendations

The length of treatment may vary. It's usually advised not to go beyond two weeks without consulting a doctor for a review. When tapering the dose, it's recommended to decrease the frequency of application to prevent sudden flare-ups rebounding.

Special Considerations for Sensitive Skin Areas

When using the cream in areas such as the face, underarms, and groin, it's important to be cautious since these parts of the body are more prone to skin thinning.

VI. Clobetasol propionate side effects

Overview of Potential Side Effects

Although Modulate 3 Cream is helpful, its effectiveness does come with the downside of causing side effects when used for an extended period of time and over extensive skin areas, which could lead to both local and systemic adverse reactions.

Local Skin Reactions: Burning, Itching, or Irritation

Skin irritation is often seen in the stages of treatment. Typically, it improves as the skin gets used to the medication over time.

Risk of Thinning Skin with Prolonged Use

Extended use of corticosteroids can lead to skin thinning or atrophy over time; this is particularly noticeable in regions such as the face.

Systemic Side Effects Due to Absorption

In some instances, steroids may enter the bloodstream and cause effects like hormonal imbalances or Cushing's syndrome. The chances of these side effects increase when the cream is applied in quantities or for prolonged periods.

Long-term Use Complications

Prolonged usage could lead to issues, like skin infections, slower wound recovery and the appearance of stretch marks.

VII. Common Side Effects of Modvate 3 Cream

List of Frequently Reported Side Effects

- Dryness or cracking of the skin

- Folliculitis (inflammation of hair follicles)

- Redness and irritation

Skin Dryness or Cracking

Excessive use or incorrect application can result in dryness that may lead to skin cracking and discomfort.

Folliculitis

Inflammation of hair follicles may happen when using dressings along with the cream.

Contact Dermatitis from Prolonged Use

Some individuals might experience contact dermatitis from using Modavate 3 Cream, which could worsen their initial skin issue in certain cases.

Changes in Skin Color at the Site of Application

Prolonged use of this product may lead to skin-lightening issues due to hypopigmentation effects for those with skin tones.


VIII. Warnings and Contraindications for Modvate 3 Cream

Contraindicated Medical Conditions

Individuals with fungal or viral skin infections should avoid using Motivate 3 Cream as it could worsen these conditions.

Allergy or Hypersensitivity to Ingredients

Individuals who have allergies to any of the ingredients in Modavate 3 Cream should refrain from using it to avoid responses that could range from slight irritation to serious anaphylaxis.

Contraindications for Use on Infected Skin

Avoid putting the cream on any areas, as it could make the infection worse or slow down its healing process. Corticosteroids weaken the system's response.

Situations Where Modvate 3 Cream Should Not Be Used

- Rosacea

- Acne vulgaris (except under medical supervision)

- Perioral dermatitis


Risk of Systemic Absorption and Its Contraindications

Individuals who have previously experienced reactions to corticosteroids or those with conditions such as Cushing's syndrome should exercise caution when using the cream due to the potential for unwanted side effects from its systemic absorption.

Clobetasol propionate alternative

  • Halobetasolo propionate (Ultravatae, Lexette),
  • fFurandrenolide (Nastro Cordran),
  • Betametasone dipropionate (Dioproene),
  • Diflorasone diacetate (Psorcon),
  • Fluocinonide (Licex),
  • Desossimetasone (Topicort).

Natural substitute for clobetasol propionate

  • Chamomile calendula,
  • Licorice,
  • Witch hazel,
  • St.Johns Wort
  • Curcuminare

IX. Interactions with Other Medications

Possible Interactions with Topical Treatments

When you apply Modvate 3 Creams, be sure to know how it may interact with the skin treatments you're using at the time. Combining skin products that have active components can result in amplified effects that can make both the positive and negative reactions stronger. For instance, pairing corticosteroids or retinoids might raise the chances of experiencing skin irritation, reduced thickness of the skin, or even absorption into your system.

Impact of Using Modvate 3 Cream with Oral Corticosteroids

Using Modulate 3 Cream along with corticosteroids needs to be approached as both types of corticosteroids are effective in reducing inflammation, but combining them could increase the chances of experiencing systemic side effects like Cushing's syndrome or adrenal suppression and imbalances in electrolyte levels. For patients who need to use both topical steroids, it's important to keep an eye out for any signs of too much corticosteroid exposure, such as sudden weight gain, swelling in the face, or fluctuations in blood sugar levels.

Effects of Combining Modvate 3 Cream with Antibiotics or Antifungals

When Modavate 3 Cream is used in conjunction with antibiotics or antifungal medications, it may occasionally. Change the appearance of skin infections. While antibiotics fight infections and antifungals, address fungal overgrowth, the immune suppressant properties of Modavate 3 Cream could impede the body's ability to combat pathogens. This becomes especially worrisome in instances of infections as the cream might worsen the situation by postponing treatment or masking signs of infection.

Guidance for Patients Using Multiple Topical Treatments

  1. When taking medications as prescribed by a healthcare provider or doctor, it is crucial to apply each treatment at different times to avoid any potential interactions and promote the best absorption of the medications.
  2. Remember to use one treatment in the morning and one at night.
  3. Make sure to wait for 30 minutes, in between applying each product to give them enough time to be absorbed effectively.
  4. Before using Modivate 3 Cream it's important for patients to talk to their healthcare provider about any treatments they may be using to prevent any potential interactions and make sure they get the most out of their treatment.

X. Storage Instructions for Modvate 3 Cream

Proper Storage Conditions to Maintain Efficacy

It's essential to store Modivate 3 Cream to maintain its effectiveness and strength over time. Keep the cream in a dry place away from sunlight or extreme heat, as exposure to light or high temperatures may reduce the potency of the active ingredient and make the treatment less effective.

Temperature and Humidity Requirements

The recommended storage temperature for Modvate 3 Cream is 15°C to 25°C (59°F to 77°F). In areas with humidity, it is important to shield the cream from moisture, as it can impact the texture and durability of the product. Storing the cream in its packaging while ensuring that the cap is securely closed will aid in preserving its quality.

Shelf Life and Expiration Details

Modivate 3 Cream usually remains fresh for about two to three years after it is made available for purchase on the market shelves. However, wisdom suggests that once the cream has been uncapped, it is best to use  it up within three months to reap its benefits. It's advisable to verify the expiry date before application and dispose of any product to prevent the usage of potentially ineffective or deteriorated medication.

Handling Precautions to Avoid Contamination

Make sure your hands are clean before applying the cream to avoid contamination. Keep the nozzle sterile by not touching your skin or any surface. Remember to close the tube after each use to maintain its cleanliness and prevent bacteria from causing skin problems if it gets contaminated.

XI. Important Precautions for Modvate 3 Cream Use

Avoiding Use on Broken or Infected Skin

Please refrain from sharing information such as identification numbers or financial details online to protect your privacy and security.

Precautions for Applying Near Eyes, Mouth, or Mucous Membranes

When using Modvate 3 Creams, make sure to keep it away from areas like your eyes or mouth and avoid contact with mucous membranes as well! If the cream happens to touch these areas accidentally, just wash it off with plenty of water to prevent any irritation or absorption of the corticosteroid, which could lead to unwanted effects such as cataracts or glaucoma, especially if it is near your eyes for an extended period of time.

Monitoring for Adverse Skin Reactions

Patients need to stay alert and keep an eye on their skin for any reactions while undergoing treatment, as these could be signs of a response to the medication or therapy being used. Signs of redness or swelling at the spot where the product was applied. Feeling an itch or a sensation of burning. The formation of pustules or blisters. If you experience any of these symptoms mentioned above while using the cream it is recommended to stop using it and seek advice, from a healthcare professional to avoid any complications.

Avoiding Overuse and Risk of Steroid Dependency

Overusing Modvate 3 Cream for a time may cause the skin to become dependent on corticosteroids for upkeep. This reliance can trigger a condition called steroid withdrawal syndrome, which shows symptoms like skin redness, burning sensation, and peeling once you stop using the treatment. To prevent this issue, it's important to follow the cream's usage and gradually reduce its application with guidance from a healthcare provider.

XII. Careful Administration of Modvate 3 Cream

Considerations for Patients with Skin Infections

When dealing with patients who have both skin infections at the time, it's important to proceed with caution when utilizing Modivate 3 Cream due to its characteristics, which may exacerbate infections further, necessitating the treatment of infections prior to starting corticosteroids such as Modivate 3 Cream. If infections persist, it may be crucial to cease using the cream and start suitable antimicrobial treatment instead.

Careful Use in Patients with a History of Allergic Reactions

Patients who have previously shown sensitivity to corticosteroids or any ingredients in the cream should refrain from using it to prevent reactions, like rashes or swelling; in case such a reaction occurs, treatment should be discontinued promptly, and medical guidance sought out for a potentially more fitting non-steroidal alternative option.

Special Instructions for Areas with Thin Skin, Such as the Face

When Modvate 3 Cream is used on areas with skin layers, like the face or neck, it carries a greater chance of causing skin atrophy and other potential side effects to occur more frequently. To minimize the risk, it is advised to apply the cream and limit its use to short periods only. Continuous application on the face may result in complications, like dermatitis or exacerbation of rosacea.

Guidelines for Using Occlusive Dressings

Using coverings on the skin can improve how Modvate 3 Cream gets absorbed. It's important to be careful when doing so. Although coverings can make the cream more powerful, in treating conditions, they also increase the chances of the cream getting into your bloodstream and causing skin reactions. Always use coverings under a doctor's guidance. Keep an eye on your skin for any signs of irritation or infection.

XIII. Administration of Modvate 3 Cream to Special Populations

Administration to Elderly Patients

Elderly individuals often have skin that can become thinner and more prone to bruising when using Modavate 3 Cream.Thus, it may be advisable to consider dosages or shorter treatment periods and watch for any signs of skin damage.

Administration to Pregnant Women and Nursing Mothers

Pregnant women should be careful when considering the use of Modvate 3 Cream during pregnancy. There is uncertainty about any harm to the fetus from corticosteroids due to possible absorption into the body systemically during pregnancy if needed and with medical oversight only. Nursing mothers should also be cautious because corticosteroids might enter breast milk and pose a risk to the baby.

Administration to Children

It is advisable to use Modvate 3 Cream in children due to their increased susceptibility to absorbing it into their system and experiencing side effects as a result of its powerful corticosteroid content, which could hinder a child's growth and development if applied over extensive areas or for extended durations of time. Moreover, it is essential that pediatric dosages are kept at the level possible, with regular monitoring being a critical factor to consider.

XIV. Overdosage of Modvate 3 Cream

Symptoms of Overdose with Topical Steroids

Overuse of Modvate 3 Cream can lead to symptoms of corticosteroid overdose, which may include:

- Skin thinning

- Striae (stretch marks)

- Telangiectasia (spider veins)

In severe cases, systemic symptoms may occur, such as high blood sugar or suppressed adrenal function.


Risks of Systemic Corticosteroid Toxicity

Rarely occurring but severe in nature is the toxicity caused by corticosteroids due to the use of potent corticosteroids topically applied to the skin. Indicators of this condition consist of weight gain, retention of fluids in the body, elevated blood pressure, and alterations in mood or behavior. It is vital to detect these signs to avert potential long-lasting health problems.

Treatment and Management of Overdose Cases

If you notice any signs of taking much of the cream product, stop using it and consult a healthcare professional for guidance on what to do next. In some instances where there is an overdose issue involved with the cream product, treatment might require measures. Sometimes discontinuing corticosteroids with the supervision of a medical professional. For cases involving side effects that affect the whole body, additional intensive treatments, like fluid control or hormonal therapy, might be needed for recovery purposes.

Recommendations for Accidental Ingestion or Excessive Application

In situations where accidental swallowing occurs and things go awry, consuming substances.

Modvate 3 Cream FAQ

Does clobetasol help hemorrhoids?

Clobetasol and similar steroids are very strong, so they are not typically prescribed for issues, like hemorrhoids or piles, in the area.

Will clobetasol propionate cause hair loss?

Hair loss or thinning might also happen. It's uncommon and estimated to affect around 1 in every 300 individuals using clobetasol cream or ointment for skin conditions related to inflammation. Clobetasol is a steroid that may not be the best choice for treating hair and scalp issues that do not involve inflammation.

Will clobetasol propionate treat an athlete's foot?

Clobetasol, a type of steroid, is commonly prescribed for managing ec​zema and various skin issues.

Will clobetasol propionate treat ringworm?

Never apply clobetasol in the groin area for ringworm, as it may alleviate itching and ringworm at first but can potentially worsen the ringworm infection significantly in the long run.

Will clobetasol propionate treat poison ivy?

Clobetasone propionate can be applied to help heal a poison ivy rash before it forms blisters or if the rash is localized to an area, and oral corticosteroids are not recommended.

Why use clobetasol propionate cream?

It helps to lessen swelling and irritation from skin issues like eczema and psoriasis by reducing skin inflammation. It belongs to a class of medicines known as steroids.

Why clobetasol propionate ointment used?

Clobetasol propionate functions as a skin remedy for managing ecze­ma and psoriasis symptoms by alleviating swelling and itchiness while addressing redness and rashes associated with these skin issues; it belongs to the category of steroid remedies.

Where is clobetasol propionate cream used for?

Clobetasol propionate ointment can be applied to the skin to help manage eczema and psoriasis symptoms like inflammation and itching caused by these skin issues—it belongs to a class of steroid medications.

When to use clobetasol propionate cream?

Clobetasol propionate ointment can be applied to the skin to help with eczema and psoriasis by reducing inflammation and alleviating itchiness and redness commonly associated with these skin issues.

Clobetasol propionate when breastfeeding?

For skin issues, apply clobetasol to your chest area. Avoid using it on the nipples if it gets on your breasts during the application process. Rinse it off thoroughly and wash your hands before nursing your baby to prevent any transfer of the medication to them. Opt for using cream instead of ointment while breastfeeding, as it can be washed off more easily.

What is clobetasol propionate for lichen sclerosis?

Clobetasol propionate is a corticosteroid known as an ultra-potent or super-potent medication. Studies indicate that using this treatment for 12 weeks can greatly alleviate symptoms of lichen sclerosis in 75% to 90 % of patients. In contrast, 10 % of patients who received a placebo ointment experienced improvements.

What is clobetasol propionate side effects?

When you first put it on your skin you may feel burning or itching sensations at the area of application like an dryness feeling, with redness as well.

What is clobetasol propionate .05 used for?

It reduces skin inflammation, helping to lessen swelling and redness and alleviate itching or skin rashes resulting from skin issues like eczema and psoriasis. This is part of a category of treatments called steroids.

What is clobetasol propionate topical solution?

It helps alleviate swelling and skin irritations, like redness and itching, from conditions such as eczema and psoriasis by reducing skin inflammation.It falls under the category of drugs known as steroids.

How to apply clobetasol propionate?

For best results, apply a layer of cream or ointment to the skin area, gently rubbing it in the direction of hair growth.

How to use clobetasol propionate on scalp?

Apply an amount of this medication to the impacted part of your scalp. Massage it gently without covering your head with any accessories, like a shower cap or bathing cap, during the treatment process. When using the shampoo, refrain from wetting your hair beforehand.

How does clobetasol propionate work?

Clobetasol is a steroid that functions by decreasing inflammation and alleviating itching and discomfort resulting from reactions or irritations; it is effective in addressing skin conditions like ec

Can clobetasol propionate be used for acne?

Clobetasol should not be applied to treat acne or skin infections caused by bacteria, fungi, or viruses (like herpes simplex, shingles, or chickenpox) as bites or stings.

Can clobetasol propionate be used on the face?

Avoid applying this medication to your face or in areas like the groin or underarms unless specifically instructed by your healthcare provider. For using the creamed products (foam/gel/lotion/spray), remember to wash your hands with soap and water both before and after applying the medication.

Can clobetasol propionate be used for jock itch?

Avoid using this medication for skin infections or issues, like burns; refrain from applying it to the face, groin, or underarms, and avoid usage if your skin is thin unless advised by your doctor.

Can clobetasol propionate be used for poison ivy?

Clobetasone propionate can be applied to alleviate a poison ivy rash if it has not blistered or is limited to a region and oral corticosteroids are not recommended.

Can clobetasol propionate be used on private parts?

This medication is meant to be applied to the skin surface and should not come into contact with your eyes, nostrils, mouth, or genital area. Avoid using it on skin that is injured by cuts, scrapes, or burns.

Can clobetasol propionate be used for ringworm?

Avoid using clobetasol in the groin area for ringworm. Although it may provide relief from itching and ringworm symptoms, it can significantly worsen the infection over time.

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