Flutivate Cream

Flutivate Cream (Fluticasone Propionate) is a topical corticosteroid prescribed to alleviate inflammation and itching due to certain skin conditions, such as psoriasis, eczema, etc.

Cutivate

Fluticasone propionate

Flutivate Cream

10g, 20g

GSK

Cream

0.05% w/w

India

Flutivate Cream

I. Introduction to Flutivate Cream

Overview of Flutivate Cream

Flutivate Cream is a cortisone medication commonly prescribed in dermatology to help with skin conditions that cause inflammation. It includes Fluticasone propionate, a man-made cortisone that helps reduce inflammation and itching linked to skin problems.

Therapeutic Classification

Flutivate Cream is a topical anti-inflammatory agent belonging to the corticosteroid class. It is used to treat skin conditions characterized by redness, swelling, and irritation.

Indications for Use

The Flutivate Cream is used to treat skin conditions, like ec‌ze‌ma and ps‌ori‌a‌sis, that can lead to inflammation and discomfort. The cream helps alleviate symptoms.

Benefits of Flutivate Cream in Dermatological Conditions

- Reduces inflammation and itching rapidly.

- Prevents exacerbation of chronic skin disorders.

- Promotes skin healing and prevents infections due to its immune-modulating effects.

II. Composition of Flutivate Cream

Active Ingredients and Concentration

Flutivate Cream contains Fluticasone propionate as its component, at a concentration usually around 0.05%. This corticosteroid is known for its ability to regulate processes in the skin.

Inactive Ingredients and Their Role

The cream's inactive components consist of water, paraffin, and cetostearyl alcohol, which play a role in ensuring the cream's stability and aiding in the delivery of the active ingredient to the specific area needing treatment.

Mechanism of Action of the Active Ingredient

Fluticasone functions by attaching to receptors in skin cells to inhibit the production of inflammatory substances, like cytokines, and diminish capillary expansion, which helps alleviate swelling and redness while reducing itching.

Fluticasone salmeterol

Fluticasone and salmeterol inhalation are prescribed to prevent asthma attacks and manage pulmonary disease (COPD). It is not meant for relief during an asthma attack; in such cases a different medication should be used instead.

Fluticasone vilanterol

The combination of fluticasone and vilanterol is prescribed to manage asthma symptoms and enhance lung function.

Flonase vs fluticasone

Fluticasone is a nasal spray medication used to alleviate allergy symptoms such as sneez­ing and nasal congestion by reducing inflammation in the nose area where breathing difficulties may occur; a known brand of this medication is Flonase.

Fluticasone vs budesonide

When Fluticasone is administered at half the dosage of Beclomethasone or Budesonide, it results in enhancements.

Fluticasone vs albuterol

Using Flovent (fluticasone) regularly can reduce the frequency and intensity of asthma episodes over time; however, it is not intended to provide relief during an asthma attack since it is not a quick relief inhaler, like Albuterol sulfate, which is classified as a short-term beta agonist (SABA).

Azelastine-fluticasone

The nasal spray that combines azelastine and fluticasone relieves symptoms like runny nose and sneezing caused by hay fever (also known as allergic rhinitis). Azelastine acts as an antihistamine that functions by blocking the effects of histamine, a substance naturally produced by the body.

Fluticasone formoterol

The use of both fluticasone propionate ICS and formoterol LABA in one inhaler to treat asthma in adults (12 years and older) proves to be a treatment choice that offers effectiveness while also promoting adherence to the treatment and compliance with international guidelines.

III. Fluticasone mechanism of action

Corticosteroid Mechanism in Skin Treatment

Flutivate Cream works as a corticosteroid by blocking the production and release of substances in the skin, preventing the system from causing excessive damage to healthy tissues.


Anti-inflammatory and Immunosuppressive Properties

Fluticasone's ability to reduce inflammation restricts the movement of cells to the inflamed area. It also aids in controlling autoimmune skin conditions such as psoriasis by regulating overactive immune responses.

Cellular Mechanism at the Affected Skin Area

Fluticasone works by decreasing the creation of enzymes and proteins that contribute to skin inflammation. It helps stabilize cell membranes while also preventing the release of histamine to relieve symptoms.

IV. Uses of Flutivate Cream

Primary Indications and Conditions Treated

Eczema

Flutivate Cream is commonly employed in treating eczema. It alleviates redness and itching and improves skin scaling, offering relief from symptoms.


Psoriasis

When dealing with psoriasis issues, the cream helps lower the production of skin cells and soothes inflammation, ultimately resulting in plaques and flakes on the skin.

Dermatitis

Flutivate proves helpful in addressing types of skin conditions, like contact dermatitis and atopic dermatitis, by calming inflammation and reducing skin irritation.

Off-Label Uses of Flutivate Cream

Vitiligo Management

Flutivate Cream is occasionally utilized off-label to address vitiligo by lessening inflammation near areas lacking pigmentation in an effort to potentially inhibit the progression of the condition.

Post-laser Therapy

After undergoing treatments such as laser therapy procedures, Flutivate might be recommended to help prevent inflammation and enhance the skin's healing process more quickly.

Pruritus Relief

Flutivate Cream can also be used in standard ways to help alleviate pruritus (itching) in different situations where the root cause is an excessive immune response.

Fluticasone for cats

Some vets suggest using a mix of fluticasone and salmeterol as bronchodilators for your feline friend's treatment plan. Your vet will chat with you about these options and prescribe suitable medications for your cat's health needs.


V. Fluticasone propionate dosage

Fluticasone dosage for adults

Adults should gently apply an amount of Flutivate Cream to the skin area once or twice a day as advised by their doctor, depending on the seriousness of the condition.

How to Apply Flutivate Cream

Before using the cream, make sure to cleanse the area that needs treatment. Then, apply a quantity of the cream to your skin and gently massage it until it is completely absorbed.


Dosage Adjustments Based on Condition Severity

For mild to moderate skin inflammation cases, applying a solution once a day may be sufficient, while severe conditions may need frequent applications, with medical supervision.

Duration of Treatment

The length of treatment usually varies from days to a week based on the specific condition being addressed to avoid skin thinning risks associated with extended use.

VI. Administration in Special Populations

Administration to Children: Safety and Precautions

When using Flutivate in children, the skin's sensitivity to corticosteroids should be considered, with caution to diminish the dosage and prevent prolonged usage.

Use in Elderly Patients: Dosage Adjustments and Sensitivities

Older individuals with skin are at risk of experiencing negative effects from treatment regimens. To minimize any complications, it is recommended to use doses and limit the duration of treatment.

Administration to Pregnant Women and Nursing Mothers: Safety Profile and Guidelines

While Flutivate Cream is deemed safe for use during pregnancy and breastfeeding, it is advisable to apply it when the benefits outweigh the risks and restrict application to specific small areas on the skin.

VII. Fluticasone cream side effects

Common Side Effects

Skin Irritation

Some individuals might encounter skin discomforts, like tingling or redness when using the product in certain areas.

Dryness

At times, Flutivate Cream may result in increased dryness that can cause flakiness or a tight feeling in the skin.

Redness

Mild redness might appear when your skin adapts to the treatment; however, this usually fades away with use.

Rare but Serious Side Effects

Hypersensitivity Reactions

In some instances, individuals may experience responses, like rashes, intense itching, or swelling that require prompt medical care.

Skin Thinning and Stretch Marks

Prolonged Flutivate usage could lead to skin thinning (atrophy), causing stretch marks to form commonly in regions with skin layers.

Fluticasone side effects long-term

Extended or excessive usage of Flutivate Cream could result in absorption throughout the body, which might lead to suppression and other effects related to corticosteroids.

VIII. Contraindications and Warnings

Absolute Contraindications

Patients should avoid using Flutivate Cream if they are allergic to Fluticasone propionate or any other ingredients in the product formulation. It is also not recommended for those who have untreated viral or fungal skin infections.

Conditions Where Flutivate Cream Should Not Be Used

- Rosacea

- Acne vulgaris

- Perioral dermatitis

Important Warnings Regarding Long-Term Use

Long-term application of Flutivate Cream can lead to irreversible skin damage, including atrophy and telangiectasia (visible blood vessels). It should be used for the shortest duration necessary to control symptoms.

IX. Fluticasone interactions

Potential Drug Interactions

When you put Flutivate Cream on your skin directly, it might react differently with drugs in your body, mainly if they get absorbed into your bloodstream. You should be careful if you use it together with medications, as it could increase the chances of side effects related to corticosteroids. Also, medicines that affect CYP3A4 enzymes could change how Fluticasone propionate is processed in your body, making it work better or less effectively. It's essential to keep an eye on things when you mix Flutivate with these medications.

Interaction with Topical and Systemic Medications

Topical corticosteroids such as Flutivate Cream might react with treatments that have alcohol in them, leading to excessive dryness or irritation issues for the skin users applying them to their skin should make sure to use them at separate times to avoid any direct interactions and reduce the chances for negative effects Combining systemic medications notably immunosuppressive drugs with Flutivate could further weaken the immune system increasing the likelihood, for infections or slower healing processes

Food and Lifestyle Considerations

While Flutivate Cream works on the skin's surface and treats issues locally, a person's diet and general well-being can impact how well it works. Taking care of your skin by keeping it hydrated and nourished can help improve its condition. Staying away from foods that cause inflammation, such as processed snacks and dairy, may help lessen skin problems. Additionally, reducing stress levels and incorporating habits like moisturizing can enhance the effectiveness of treatment.

X. Precautions and Careful Administration

Skin Sensitivity and Flare-ups

Individuals with skin or who are prone to skin reactions should use Flutivate Cream carefully. Be extra cautious when applying it to areas prone to flare-ups or sensitivity issues. Before using the cream on areas of the skin, it is advised to perform a patch test to check for any adverse reactions or allergies. If you experience heightened irritation or redness after application, stop using the cream and seek guidance. Persistent or severe reactions may indicate a reaction or overuse.

Precautionary Measures for Application on Broken or Infected Skin

It's important not to use Flutivate Cream on wounds or areas with skin infections unless advised by a healthcare provider. Applying corticosteroids on infected or broken skin can worsen the situation by weakening the local immune response and promoting the growth and spread of infections. It's crucial to make sure that any infection is properly treated before starting Flutivate therapy.

Fluticasone propionate cream on eyelids

Avoid applying the cream or ointment to your eyes or on your eyelids, as it may cause irritation or discomfort in those areas. Fluticasone, a type of steroid, works by decreasing inflammation in the skin, which can assist in controlling and alleviating your eczema symptoms.

Fluticasone propionate cream for face

Avoid applying fluticasone to your face unless specifically advised by a doctor. The skin on your face is sensitive, and any thinning or damage caused by fluticasone cream would be quite noticeable.

Sun Exposure and Use of Sunscreen

When using Flutivate Cream in sunlight, the skin may become more susceptible to damage due to the thinning effects of corticosteroids and increased vulnerability to UV rays. It is recommended that individuals apply an SPF spectrum sunscreen before going outside and wear protective clothing to reduce sun exposure risks. It is important to avoid tanning beds and prolonged exposure to the sun for skin protection.

Handling Precautions and Safe Use Instructions

Using Flutivate Cream correctly is important for both its effectiveness and safety reasons. Remember to wash your hands after applying the cream to avoid contamination. Be careful not to get the cream in your eyes, nose, or mouth, as it could cause irritation. Apply the cream in amounts on the affected areas as using too much can adversely affect your body. Always close the tube after each use to keep it effective and free from contamination.

XI. Storage Instructions for Flutivate Cream

Optimal Storage Conditions

To maintain its effectiveness, Store Flutivate Cream in a dry place away from sunlight or extreme heat sources. The recommended storage temperature is between 20°C and 25°C (68°F and 77°F). Keeping the cap closed is important to prevent air exposure that could lead to drying out or contamination of the product.

Shelf Life of the Product

Flutivate Cream usually remains effective for 2 years from the manufacturing date when appropriately stored; it's essential not to use it after expiry as its strength may weaken and the composition could alter, which might cause skin reactions.

Instructions for Safe Disposal After Use

It's important to handle leftover, expired Flutivate Cream properly to prevent harm to the environment and others around us. Make sure not to throw the cream in household trash or flush it down the toilet; follow your area's guidelines for disposing of medications responsibly or return any unused product to a pharmacy for safe disposal. By doing so, we can help protect our surroundings from pollution and ensure the safety of everyone.

XII. Overdosage of Flutivate Cream

Signs and Symptoms of Overdosage

Using Flutivate Cream excessively or applying it on areas can cause an overdose of corticosteroids throughout the body despite it being a remedy. Symptoms indicating an overdose encompass skin thinning, bruising, and easily enhanced facial hair. The appearance of marks. In instances adrenal suppression might manifest as tiredness, weakness and low blood pressure.

Potential Systemic Effects of Excessive Use

Using Flutivate Cream for a period or in excess can result in the absorption into the system, leading to symptoms akin to those observed with corticosteroid consumption like Cushing's syndrome manifestations such as weight gain and high blood pressure along with mood and behavior changes could be seen as well. Patients who apply the cream over areas or for a prolonged duration are especially vulnerable to these effects; hence monitoring their condition may be necessary, in these instances.


Emergency Management of Overdose

Suppose someone takes much of the cream by mistake. Shows signs of an overdose. They should stop using it right away and get medical help as soon as possible. Treatment might include managing the symptoms and for cases dealing with insufficiency. Its recommended to reduce the use of the cream over time, than stopping suddenly if it has been used excessively to prevent any withdrawal symptoms.

XIII. Administration in Specific Conditions

Special Considerations for Patients with Pre-existing Skin Conditions

Individuals dealing with standing or skin problems, like eczema or psoriasis, may need customized treatment strategies when utilizing Flutivate Cream to prevent skin thinning and reduce the chances of secondary infections from occurring due to overuse. During instances intermittent or pulse therapy could be an approach to manage these risks effectively. Furthermore, it is crucial to observe any reactions to guarantee that the cream delivers the expected therapeutic advantages without worsening the primary issue.

Impact on Immunocompromised Patients

Individuals with weakened systems, like those receiving chemotherapy or medications, should exercise care when using Flutivate Cream. This is because their immune systems are less effective in fighting off infections, and the immuno-suppressing effects of Fluticasone can potentially elevate the risk further. Medical professionals must oversee the treatment to weigh the advantages of inflammation reduction against the possibility of heightened infection risks. To safeguard patients against secondary skin infections, it may be required to introduce antimicrobial agents.

Flutivate Cream FAQ

Fluticasone how long to work?

This medicine won't show results; you might notice a change within 12 hours of starting treatment. It could take a few days to experience its full benefits. If your symptoms don't improve after a week or if they get worse, suspend the use of this medication. Seek advice from your doctor or pharmacist.

How fluticasone works?

Fluticasone belongs to a group of medicines known as corticosteroids. These medicines function by preventing the release of substances responsible for triggering allergy symptoms.

Can fluticasone cause high blood pressure?

Most individuals who take this medication do not experience any effects. However, it is possible that this medication could increase blood pressure. It is recommended that you monitor your blood pressure and inform your doctor if the readings are elevated. In some cases, this medication might lead to a severe aggravation of breathing difficulties or asthma right after its use.

Can fluticasone cause headaches?

The use of fluticasone nasal spray might lead to some side effects that you should discuss with your doctor if they persist or become bothersome, such as headaches, dryness, and stinging or burning sensations in the nose.

Can fluticasone propionate cause weight gain?

Flonase Allergy Relief nasal spray containing fluticasone does not lead to weight gain. It could be a choice for managing hay fever or other allergy symptoms when weight gain is a worry.

Can fluticasone cause anxiety?

Fluticasone is a cortisone medication that requires a prescription to address inflammation in the body's tissues. Individuals experiencing anxiety should consider alternatives when using fluticasone due, to its side effects—those using it for respiratory issues.

Can fluticasone raise blood pressure?

Most individuals who take this medicine usually do not experience any effects associated with it; however, it may lead to an increase in your blood pressure levels over time. Monitor your blood pressure and inform your healthcare provider if the readings indicate levels. In cases this medication could potentially trigger a severe deterioration, in breathing or worsen asthma symptoms immediately after use.

Are fluticasone and symbicort the same?

Symbicort contains budesonide, whereas Advair contains fluticasone. Additionally, Both Symbicort and Advair have a lasting bronchodilator to help keep the airways open; Symbicort includes formoterol, while Advair includes salmeterol.

Are fluticasone and azelastine the same?

Azelastine is a type of antihistamine that operates by obstructing the activity of components known as histamines, which trigger allergic reaction symptoms. Fluticasone is categorized under corticosteroids and diminishes inflammation and swelling within the nasal passages.

Are fluticasone and mometasone the same?

Fluticasone propionate is more targeted towards the receptor than mometasone furoate, which also demonstrates effects on other nuclear steroid receptors.

Are fluticasone and flovent the same?

Flovent (fluticasone) is an inhaled cortical steroid treatment prescribed for individuals aged 4 and above with asthma. When used daily as directed, it reduces lung inflammation and maintains airways. Regular use can effectively reduce both the frequency and intensity of asthma attacks.

Are fluticasone and flonase the same?

Fluticasone is a medication in nasal spray form that is used to alleviate symptoms associated with allergies, such as nasal congestion or runniness, by reducing inflammation in the nasal passages to help improve breathing ease. Flonase is a popular brand of fluticasone.

Will fluticasone raise blood pressure?

Most individuals who take this medicine do not experience any effects. However, it's possible that this medicine could elevate your blood pressure levels. Be sure to monitor your blood pressure and inform your physician if you notice readings. In some cases, this medication might lead to a severe exacerbation of breathing difficulties or asthma right after administration.

Will fluticasone keep me awake?

Patients suffering from rhinitis find that their sleep quality improves when they use fluticasone at recommended doses.

Will fluticasone raise blood sugar?

An individual with type 3 diabetes and asthma experienced a one-percent rise in hemoglobin (% HbaIC). This increase, coupled with glucosuria, was observed in someone using a dosage of inhaled fluticasone propionate (FP) totaling two milligrams per day.

Which is stronger fluticasone or triamcinolone?

Propionate (FP) is recognized to have four times higher application strength than triamcinolone acetonide ( TAA ).

Which is better fluticasone or budesonide?

In treating asthma with medications, fluticasone, compared to beclomethasone and budesonide at half the daily dosage, shows similar effectiveness levels or even better outcomes in some cases, but it might result in more instances of sore throat when administered at equivalent doses.

Which is better fluticasone or azelastine?

Due to its side effects and safety profile in children as well as patients with glaucoma and cataracts

Which is better fluticasone or ipratropium?

Atrovent (ipratropium bromide ) and Flonase (fluticasone ) are prescribed to manage symptoms of non-rhinitis. Atrovent Nasal Spray and Flonase are medications. Atrovent Nasal Spray is classified as an anticholinergic, while Flonase is a medication.

Which is better fluticasone or mometasone?

Mometasone furoate showed effectiveness compared to fluticasone propionate when used at the dosages.

When does fluticasone start to work?

This medicine won't show results; you might notice an impact within 12 hours of beginning treatment. It could take a few days to experience the full benefits. If your symptoms do not improve after a week or if they worsen, discontinue using this medication and seek advice from your doctor or pharmacist.

What fluticasone propionate cream used for?

Fluticasone topical is prescribed to help decrease swelling and alleviate itching and redness. It's also used to treat skin problems, like psoriasis (characterized by patches with scales) and eczema (causing dryness and itchiness in the skin).

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