Avonza, Lamivudine/ Tenofovir/ Efavirenz

Avonza

Lamivudine/ Tenofovir disoproxil fumarate/ Efavirenz

Avonza

30

Mylan Pharmaceuticals

tablet

Lamivudine 300 mg / Tenofovir disoproxil fumarate 300 mg / Efavirenz 400 mg

India

Lamivudine

Uses

Lamivudine is used together with other anti-retroviral medicines in the treatment of HIV-1 infection and chronic hepatitis b virus (HBV) infection.

How it Works

Lamivudine is a nucleoside analogue, it works by destroying CD4 helper cells and stopping the HIV virus from spreading.It blocks the action of the Reverse Transcriptase enzyme which helps the virus replicate, this results in destroying the viral HIV chain

Common Side effects

Patients who take Lamivudine may suffer from such side effects;

Fatigue,
Headache,
Insomnia,
Dyspepsia,
Nausea,
Cramps and Abdominal pain,
Dizziness,
Ear and/or Nasal infection,
Sore throat,
Skin rash,
Muscle pain,
Fever,
Chills,
Diarrhoea

Efavirenz

Uses

Efavirenz is an antiretroviral medicine; Efavirenz It is used in the treatment of human immunodeficiency virus (HIV) infection. Efavirenz slows the progress of HIV infections, however it is not a cure, it just controls the HIV virus and prevents it from spreading

How it Works

Efavirenz treats HIV infections by inhibiting viral reverse transcriptase and DNA polymerases. The HIV virus needs An enzyme called RT (reverse transcriptase) to replicate its DNA in order to spread and infect more cells. Efavirenz works by blocking the reverse transcriptase, this then helps to terminate the DNA chain and prevent the virus from multiplying. Efavirenz slows down the HIV Infection progress in the body but it is not a cure.

Common Side effects

Patients who take Efavirenz may suffer from such side effects;

Nausea,
Fatigue,
Vertigo,
Lipodystrophy,
Concentration difficulties,
Rash,
Headache,
Decrease in granulocyte count,
Insomnia (difficulty in sleeping),
Sleepiness,
Vomiting,
Allergic reaction,
Abnormal dreams,
Increased liver enzymes,
Anxiety,
Fever,
Itching,
Difficulty in paying attention,
Increased triglyceride level in blood

Tenofovir

Uses

Tenofovir is used in the treatment of chronic hepatitis b virus (hbv) infection and hiv infections.

How it Works

Tenofovir is an antiretroviral medicine known as nucleoside reverse transcriptase inhibitors (NRTIs). Tenofovir slows the progress of HIV infection, but it is not a cure. Tenofovir is used with other medicines in a combination therapy. Tenofovir works by by stopping the virus HIV from copying (replicating) itself. Tenofovir works by stopping the hepatitis B virus from multiplying further, this reduces the amount of the virus in your body.

Common Side effects

Patients who take Tenofovir may suffer from such side effects;

Abdominal pain,
Vesicobullous reaction
Fatigue,
Weakness,
Headache,
Nausea,
Diarrhoea,
Muscle pain,
Pain,
Dizziness,
Depression