Prazimec Oral Paste

Prazimec Oral Paste for Horses (Ivermectin/Pyrantel) is prescribed to treat and manage internal parasites, such as tapeworms, lungworms, bots, etc.

Generic Equimax Horse Wormer Gel

Ivermectin/ Pyrantel

Prazimec

6.42g

Vetbiochem, Cipla

Oral Paste

Ivermectin 18.7 mg / Pyrantel 140.3 mg

India

Out of Stock.

Prazimec Oral Paste

Introduction

Overview of Prazimec Oral Paste

Prazimec Oral Paste is a meticulously formulated therapeutic agent engineered to provide comprehensive oral care. Its design marries efficacy with patient-centric safety, ensuring an optimal balance between rapid action and sustained relief. Short in purpose yet vast in utility, this paste exemplifies modern pharmaceutical craftsmanship.

  • Formulated with precision.
  • Targeted for a myriad of oral conditions.
  • Combines scientific rigor with clinical practicality.

Indications and Target Patient Populations

The Prazime​ Oral Paste for Horses (containing Iver​me​ctin and Pyra​ntel​) is recommended for the treatment and control of parasites, like tapeworm​ infes​ta​tions​​​​​​​​​​​​​​​​ ​​in ​​horses.


Composition and Formulation

Active Ingredients and Their Roles

Prazimec typically contains a combination of two active ingredients:

  • Praziquantel: This targets tapeworms.
  • Abamectin (or Ivermectin in some products): This targets a broader range of internal parasites, including roundworms and bots.


Inactive Ingredients: Binders, Preservatives, and Flavoring Agents

Complementing the active constituents are meticulously selected inactive ingredients. These excipients enhance stability, palatability, and overall patient compliance. Their roles include:

  • Binders that ensure uniform consistency.
  • Preservatives to forestall microbial contamination.

The interplay between these compounds results in a formulation that is not only efficacious but also patient-friendly.

Pazimec Oral Paste Mechanism of Action

Praziquantel Mechanism of action

  • It enhances the ability of the parasite's cell membranes to allow calcium ions to pass through easily.
  • The sudden increase in calcium levels triggers muscle contractions. It eventually leads to the parasite becoming paralyzed.
  • It also harms the shell of the parasite, making it easier for the host's immune system to attack it.  
  • It basically interferes with the parasite's capability to regulate its conditions, ultimately causing its death.


Abamectin Mechanism of Action

  • Mostly focusing on the nervous system of creatures without a backbone.
  • They boost the function of chloride channels activated by glutamate in the nerve and muscle cells of parasites.  
  • This results in a surge of chloride ions entering the cell. This leads to hyperactivity in the nerve or muscle cells.   
  • The outcome is the parasite becoming paralyzed and eventually succumbing to its demise.

Approved Uses and Off-Label Applications

It is employed to manage and regulate parasites in animals, chiefly horses, such as tapeworm infestations, along with roundworm and bot infections.


Off-Label Uses 

Off-label prescribing is common, and in some cases, it can be a necessary and appropriate practice. Doctors may prescribe a drug off-label when they believe it is the best available treatment option for a patient, especially when other approved treatments have failed. However, off-label use also carries risks, as the drug may not have been thoroughly studied for the specific use, dosage, or population.

Dosage and Administration

Standard Dosage Guidelines and Frequency

The administration of Prazimec Oral Paste is predicated on meticulously established dosage guidelines. The standard regimen is designed to optimize therapeutic outcomes while minimizing potential adverse effects. Key recommendations include:

  • Application frequency is tailored to the severity of the condition.
  • Precise dosing to ensure localized action.
  • Regular intervals to maintain consistent therapeutic levels.

These guidelines are intended to maximize efficacy and safeguard patient well-being.

Step-by-Step Administration Techniques

A systematic approach is essential for the effective use of Prazimec Oral Paste. The administration technique encompasses a series of methodical steps:

  • Cleanse the oral cavity thoroughly.
  • Apply a measured quantity of paste directly to the affected area.
  • Gently massage the paste into the mucosal tissue.
  • Allow the formulation to remain undisturbed for optimal absorption.

Short yet deliberate steps, when executed meticulously, ensure maximal therapeutic benefit.


Side Effects and Safety Profile

Common Side Effects

Rare and Serious Adverse Reactions

Breed Sensitivities:

It is crucial to note that certain dog breeds, such as Collie-type breeds, may exhibit heightened sensitivity to medications containing avermectin (such as abamectin or ivermectin).


Warnings, Contraindications, and Precautions

Key Warnings and Risk Factors

The utilization of Prazimec Oral Paste is accompanied by several imperative warnings. A confluence of risk factors, including pre-existing conditions and concurrent medications, necessitates cautious administration. Short warnings carry substantial clinical importance.

  • Risk of hypersensitivity reactions.
  • Potential exacerbation of pre-existing mucosal conditions.
  • Interactions with other topical agents.

It is paramount to comprehend these risks in their entirety to preempt inadvertent complications.


Drug Interactions and Compatibility

Praziquantel Interactions

Abamectin Interactions

Medications that block P gp may enhance the absorption of abamectin. This could result in elevated levels in the bloodstream, which may raise the likelihood of toxicity occurring. Due to the effects of Abamectin it is important to exercise caution when using other medications that may also impact the nervous system.

Overdosage Management

Recognizing Signs and Symptoms of Overdosage

 Supportive Care and Follow-Up Recommendations

After initial emergency management, supportive care becomes a cornerstone of recovery. Follow-up protocols are integral, ensuring that any residual effects are promptly addressed. Recommendations include:

  • Scheduled re-evaluations to monitor recovery.
  • Adjunctive therapies to support mucosal healing.
  • Patient education on recognizing delayed adverse effects.

Such comprehensive follow-up strategies ensure that overdosage is managed holistically and effectively.


Storage and Handling Precautions

Optimal Storage Conditions and Shelf Life

The preservation of Prazimec Oral Paste's integrity is contingent upon adherence to optimal storage conditions. Temperature, humidity, and light exposure are critical factors that influence shelf life. Best practices include:

  • Storing in a cool, dry environment.
  • Avoidance of direct sunlight and excessive moisture.
  • Regular verification of expiration dates.

Meticulous storage is indispensable in maintaining the formulation's stability and therapeutic efficacy.

Handling Precautions to Maintain Product Integrity

Proper handling of Prazimec Oral Paste is paramount to ensuring its clinical performance. The product should be manipulated with care, employing aseptic techniques where applicable. Handling precautions include:

  • Minimizing exposure to fluctuating environmental conditions.
  • Avoiding contamination through proper hygiene practices.
  • Utilizing appropriate applicators to ensure consistent dosing.

Such precautions safeguard the product's integrity from production to application.

Safe Disposal of Unused or Expired Medication

The proper disposal of unused or expired Prazimec Oral Paste is an essential component of environmental stewardship and patient safety. Disposal protocols must adhere to regulatory guidelines and local ordinances. Key recommendations include:

  • Returning expired medication to authorized disposal centers.
  • Adhering to community-based hazardous waste management programs.
  • Preventing accidental exposure by securing disposal containers.

Implementing rigorous disposal measures minimizes environmental impact and mitigates potential risks associated with improper handling.

Prazimec Oral Paste FAQ

What is pyrantel used for?

Many people use this medicine for treating worm infections, like pinworms and roundworms as hookworms. Pyrantel is part of a group of medications called anthelmintics that work by immobilizing the worms and helping the body get rid of them through bowel movements.

How long does pyrantel take to deworm?

1-2 hrs

Is pyrantel better than mebendazole?

Both medications have shown success in treating enterobiasis.

Is pyrantel a good dewormer?

Many individuals view Pyrantel as a solution for getting rid of parasites as one dose is enough to effectively treat the infection.

Which is better, pyrantel or albendazole?

Albenbazole has a success rate of 72% whereas Pyrantel Pamoate shows an effectiveness rate of 32%.

What worms does pyrantel not treat?

Doctors often suggest Pyrantel pamoate for dealing with worm infections like hookworm and Ascaris. Its ability to treat trichuriasis may have some limitations.

How to use ivermectin for dogs?

You can choose to give Ivermection in forms, like tablets or chewable options

What is ivermectin used for?

People often receive Ivermectin to treat conditions like river blindness (known as Onchocerciasis) and infections caused by threadworms in the intestines known as strongyloidiasis. It's a solution for worm infestations.

Can ivermectin paste be absorbed through the skin?

When Ivermectin is administered topically only a minimal quantity penetrates the bloodstream with P glycoprotein serving as a protector for the blood brain barrier to hinder the buildup of Ivermectin in brain tissue.

Can I give my dog ivermectin paste?

You can also use it in medications that help prevent heartworm in dogs.

Can you give ivermectin to dogs without a vet?

Many dogs can tolerate Ivermection well without any issues but its crucial to adhere to your vets guidance when giving it to them.

How much ivermectin to give a dog for mange?

Prescribe 200 micrograms of Ivermection, per kilogram through an injection for 2 to 5 sessions with a two week gap between each session has proven effective and often results in recovery outcomes.

What kind of parasites does ivermectin cure?

The use of Ivermection has proven effective, in treating conditions such as strongyloidiasis and ascariasis caused by parasites and in managing skin issues, like scabies and larva migrans well as certain infections including filariasis and onchocerciasis.

Is ivermectin a steroid or antibiotic?

Ivermection is not categorized as a steroid or an antibiotic.

Is ivermectin antifungal?

No

Does ivermectin stop itching in dogs?

Yes

How much ivermectin paste can I give my cat?

Its often recommended to give a cat 24 micrograms per kilogram of its weight.

Is ivermectin harmful to dogs?

When given in amounts and supervised by a veterinarian or animal healthcare provider ivermection is generally regarded as safe for dogs. It has shown great success in treating different parasites.

What breed of dogs cannot take ivermectin?

Certain breeds of dogs, like collies, sheepdogs or their mixed counterparts often show increased sensitivity, to ivermection compared to breeds.

How to know if ivermectin is working?

After you start taking Ivermectin medication, you will gradually start to feel its effects. It might take a while before you begin to see an improvement in your symptoms.

What plant is ivermectin made from?

Streptomyces avermitilis

What infections does ivermectin treat?

Ivermectin is commonly relied upon by individuals to address instances of river blindness triggered by threadworms and various worm infestations due to its efficacy.

Is ivermectin safe for human skin?

Yes

Can ivermectin cure mange?

Yes

How long does it take for itching to stop after ivermectin?

After getting rid of the mites with medication treatment, itching may persist for weeks.

How many times should I give ivermectin to my dog?

Monthly

Can I put ivermectin on my cat for fleas?

Yes

How long does it take for ivermectin to start killing parasites?

Immediately

Can you use ivermectin on dogs for fleas?

Although fleas and ticks may not look like worms, at first glance,​ ​it is possible to get rid of these parasites by using treatments and options that also target ear mites simultaneously.

Can I give ivermectin paste to my dog?

Ivermectin is commonly used in animal care and veterinary medicine to treat parasites in animals such as dogs and is also effective in preventing heartworm infections.

Can I deworm my dog with ivermectin?

At times, there are individuals who view ivermectin as a medicine for treating worms in dogs.

Is ivermectin painful for dogs?

When given correctly to dogs, Ivermectin is generally deemed safe. Incorrect dosages can result in reactions.

What is the natural source of ivermectin?

S.avermictilils is identified as the source of Ivermectin discovered.

Can Ivermectin treat lice?

Yes

Is ivermectin a steroid or antibiotic?

When it comes to sorting medications, Ivermectin is not considered a steroid or an antibiotic. It belongs to the group of drugs used to treat infections.

Can ivermectin paste be absorbed through the skin?

When ivermeсtin is administered topically to the skin, it gets absorbed into the body system through usage, indicating that P glycoprotein (PGP) has a role in protecting the blood-brain barrier and preventing the accumulation of ivermeсtin in brain tissues.

Does ivermectin stop itching in dogs?

Yes

What parasites does ivermectin treat?

It is often used to treat worm infections such, as Onchocerciasis and Ascariasis as to tackle problems, like Pediculosis (lice infestation).

How much ivermectin paste can I give my cat?

24 µg/kg of body weight

Is ivermectin good for fleas and ticks?

Not as efficient as other medications.

Can I give ivermectin paste to my dog?

One could also use it in medicines to protect dogs from heartworm infections.

How quickly does ivermectin work for mange?

3 weeks

What is pyrantel used for?

This medicine is commonly prescribed for treating worm infections, like pinworms and hookworms, by paralyzing the worms and helping the body eliminate them through bowel movements.

How long does pyrantel take to deworm?

1-2 hrs

Is pyrantel better than mebendazole?

Both medications have shown success in treating enterobiasis.

Is pyrantel a good dewormer?

Pyrantel is often viewed as a solution for getting rid of parasites because typically one dose is enough to treat the infection.

Which is better, pyrantel or albendazole?

Albenzel has a success rate of 72% whereas Pyrantel Pamoate demonstrates an efficacy rate of 32%.

What worms does pyrantel not treat?

Doctors often suggest Pyrantel pamoate, for dealing with worm infections, like hookworm and Ascaris. Its ability to treat trichuriasis might have its constraints.

How to use ivermectin for dogs?

You have the option to administer Ivermection in forms such, as tablets or chewable options; alternatively you can opt for a liquid. 

What is ivermectin used for?

Patients often receive Ivermectin to treat conditions like river blindness (known as Onchocerciasis) and infections caused by threadworms in the intestines called strongyloidiasis. It is commonly used to address worm infestations in the body.

Can ivermectin paste be absorbed through the skin?

When Ivermectin is administered topically, only a small portion passes into the bloodstream, where P glycoprotein acts as a protector for the blood-brain barrier, preventing the buildup of Ivermectin in brain tissue.

Can I give my dog ivermectin paste?

You can also use it in medicines that help prevent heartworm in dogs.

Can you give ivermectin to dogs without a vet?

Many dogs can tolerate Ivermectin well with no issues, so it is crucial to carefully follow the guidance of your vet when giving it to them.

How much ivermectin to give a dog for mange?

Giving 200 micrograms of Ivermectin per kilogram subcutaneously for 2 to 5 sessions with a two-week gap between each session has proven effective and often results in recovery outcomes.

What kind of parasites does ivermectin cure?

The use of Ivermection treatment has proven effective in treating conditions such as strongyloidiasis and ascariasis caused by parasites and managing skin issues like scabies and larva migrans well as specific infections including filariasis and onchocerciasis.

Is ivermectin antifungal?

No

Does ivermectin stop itching in dogs?

Yes

How much ivermectin paste can I give my cat?

One typical recommendation is to give a dose of 24 micrograms, per kilogram of a cats body weight.

Is ivermectin harmful to dogs?

When given in amounts and supervised by a veterinarian or animal expert ivermection is generally regarded as safe, for dogs. It has shown great success in treating a range of parasites.

What breed of dogs cannot take ivermectin?

Certain dog breeds, like collies, sheepdogs or their mixed counterparts often show increased sensitivity, to iverme‌ctin compared to breeds.

How to know if ivermectin is working?

When you start taking Ivermenctin medication for your symptoms it may take some time before you notice any changes in how you feel. Eventually you will start to see improvements over time.

What plant is ivermectin made from?

Streptomyces avermitilis

Can ivermectin cure mange?

Yes

Can I deworm my dog with ivermectin?

At times, individuals may view ivermectin as a drug employed for deworming dogs.

Is ivermectin painful for dogs?

When given correctly to dogs, Ivermectin is generally seen as safe. Mistakes in dosage can result in reactions.

Can Ivermectin treat lice?

Yes

Is ivermectin a steroid or antibiotic?

When it comes to sorting medications Ivermeсtin isn't labeled as a steroid or an antibiotic. It belongs to the group of drugs used for treating infections.

Does ivermectin stop itching in dogs?

Yes

What parasites does ivermectin treat?

It is often used to treat worm infections such as Onchocerciasis and Ascariasis and to combat problems like Pediculosis (lice infestation) and scabies ( infestation).

How much ivermectin paste can I give my cat?

24 µg/kg of body weight

Can I give ivermectin paste to my dog?

One could also use it in medicines to protect dogs from heartworm infections.

How quickly does ivermectin work for mange?

3 weeks

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