Domperidone
Uses
Domperidone is used in the treatment of Nausea and vomiting.
How it Works
Domperidone helps to stimulates the release of acetylcholine, a chemical messenger that can increase the motility of the intestine. Domperidone then allows the food in the stomach to go/move through the digestive system more quickly. This helps to stop feeling sick and vomitting symptoms.
Common Side effects
Patients who take Domperidone may suffer from such side effects;
Dry mouth
Fainting,
Palpitations
Headaches,
Diarrhoea
Cinnarizine
Uses
Cinnarizine is used in the treatment of problems affecting the inner ear and balance, such as dizziness and sickness and preventing travel sickness.
How it Works
Cinnarizine is known as a non-competitive antagonist of smooth muscle contractions caused by various vasoactive agents for example like histamine. Cinnarizine selectively inhibits Ca influx into depolarised cells, thereby reducing free Ca ions available for the induction and maintenance of contraction. Cinnarizine works by preventing constriction of the blood vessels of the inner ear. This improves the microcirculation of the ear.
Common Side effects
Some of the potential side effects of Cinnarizine can include the symptoms below;
Sleepiness,
Nausea,
Weight gain,
Dyspepsia.
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