DOSTINEX DOSTINEX [cabergoline], marketed by Pharmacia & Upjohn is a dopamine receptor agonist which works by stimulating a part of the brain that can decrease the production of the hormone prolactin that causes milk production. DOSTINEX is primarily indicated for the treatment of hyperprolactinemia, either idiopathic or due to pituitary adenomas. With regards to hyperprolactinemia, it is way beyond drugs like Parlodel (Bromocriptine). It induces a complete biochemical response and shows much better clinical efficacy and at the same time was better tolerated than bromocriptine in the majority of patients. Hyperprolactinemia It is a condition seen in females in which

ARIMIDEX Arimidex [Anastrozole] marketed by AstraZeneca Pharmaceuticals LP is a drug indicated in the treatment of adjuvant treatment [treatment following surgery with or without radiation] of postmenopausal women with hormone receptor-positive early breast cancer. It decreases the amount of estrogen in the body. It is chemically described as 1, 3-Benzenediacetonitrile, a, a, a', a'- Tetramethyl-5-(1H-1, 2, 4-triazol-1-ylmethyl). Estrogen receptor positive breast cancer: The estrogen receptor (ER) is a member of the nuclear hormone family of intracellular receptors which is activated by the hormone 17β-estradiol (estrogen). The main function of the estrogen

RETIN-A Retin-A [Tretinoin], Gel, Cream, and Liquid, marketed by OrthoNeutrogena, a division of Ortho-McNeil Pharmaceuticals, Inc is a 3, 7-dimethyl-9-(2, 6, 6-trimethyl-1-cyclohexenyl) -nona-2, 4, 6, 8-tetraenoic acid. Chemically, Retin-A [Tretinoin] is all-trans-retinoic acid. It is used in the treatment of acne vulgaris and keratosis pilaris. Acne vulgaris: Well, almost each and everyone has some other the time in their adolescent suffered from acne vulgaris, commonly called pimples. What is acne exactly? Our skin especially, over the face has a structure called as the pilo-sebaceous unit [

PREMARIN Premarin [conjugated estrogen] manufactured by Wyeth Pharmaceuticals, is been marketed commercially since 1942. It is primarily used in treating post menopausal symptoms. But what exactly is Premarin? Premarin is a mixture of conjugated equine estrogens obtained exclusively from natural sources, occurring as the sodium salts of water-soluble estrogen sulfates blended to represent the average composition of material derived from pregnant mares’ urine. It is a mixture of sodium estrone sulfate and sodium equilin sulfate. It contains as concomitant components, as sodium sulfate conjugates, 17 -dihydroequilin.-estradiol, and 17 -dihydroequilin, 17  Now, what is estrogen? Estrogen is hormone whose

Nexium [Esomeprazole] is a bis (5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-1-yl) magnesium trihydrate, developed and marketed by AstraZeneca This compound helps is in reducing or rather inhibits gastric acid secretion. Esomeprazole is the S-isomer of omeprazole, which is a mixture of the S- and R- isomers, meaning it is one of the two stereo-enantionmers in omeprazole. Esomeprazole was the third biggest selling pharmaceutical drug in the world for 2005, totaling US$ 5.7 billion in sales. Nexium [Esomeprazole] is a proton pump inhibitor that suppresses gastric acid

Avodart [Dutasteride], marketed by GSK, is a 5-alpha-reductase inhibitor used in the treatment of benign prostatic hypertrophy in men with enlarged prostate. Avodart [Dutasteride], blocks the action of the 5-alpha-reductase enzymes that convert testosterone into dihydrotestosterone (DHT). Avodart [Dutasteride] inhibits both isoforms of 5-alpha reductase [Type 1 and Type 2] unlike finasteride, a drug belonging to the same class of drugs but inhibiting only one form of 5-alpha reductase. It is a competitive and specific inhibitor of 5-alpha-reductase enzyme. Avodart [Dutasteride] helps improve urinary flow and may also reduce for a prostatic

Xenical [Orlistat] marketed by Roche Labs is a drug designed to treat obesity. Its primary is preventing the absorption of fats from the human diet, this leads to decrease in calorific intake. In plain language it blocks some of the fat that we eat thereby keeping it from being absorbed by the body. Xenical is used together with a reduced-calorie diet and weight maintenance to treat obesity in people with certain risk factors (such as diabetes mellitus, high blood pressure, and atherosclerosis, family history of stroke, heart attack, and high serum cholesterol and serum triglycerides. But why do we

MELLERIL Melleril [Thioridazine] is anti-psychotic drug marketed by Novartis. It is a low potency 2-methylmercapto-10-[2-(N-methyl-2-piperidyl) ethyl] phenothiazine having marked anticholinergic action. It produces the lowest incidence of extra-pyramidal side effects; otherwise all its other effects are similar to phenothiazines. This drug however has a bad reputation to cause cardiac toxicity and retinopathy hence its use is reserved in those cases which do not respond to the regular anti-psychotic drugs or those who have contraindications for the same. Melleril [Thioridazine] is mainly indicated in schizophrenics and psychosis. However in high doses

Lipitor Lipitor [atorvastatin] is a lipid lowering agent marketed by PFIZER. It is a synthetic compound of the statin group of drug which helps in lowering the cholesterol levels in the blood. [Lipid lowering agent] With 2006 sales of US$12.9 billion under the brand name Lipitor, it is the largest selling drug in the world Lipitor [atorvastatin] is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A [HMG-CoA] reductase, which catalyzes an early, rate limiting step in cholesterol biosynthesis. Lipitor [atorvastatin] inhibits this rate-determining enzyme located in hepatic tissue that produces mevalonate, a small molecule

IMITREX [Sumatriptan] is indicated in the use acute treatment of migraine. Migraine: Migraine, the most common cause of headache, afflicts approximately 15% of women and 6% of men. It is a vascular headache, comes in attacks A useful definition of migraine is a benign and recurring syndrome of headache, nausea, vomiting, and/or other symptoms of neurologic dysfunction in varying admixtures. Migraine can often be recognized by its activators (Red wine, menses, hunger, lack of sleep, glare, estrogen, worry, perfumes, let-down periods) and its deactivators (sleep, pregnancy, exhilaration, triptans). Severe headache attacks, regardless of cause, are more likely to