Omperazole Paste Syringe

Omeprazole Oral Paste Syringe for Horses is prescribed to treat and prevent gastric ulcers.

Generic Gastrogard

Omperazole

Lomac Equine

14 x 6.15g

Cipla

Syringe

37%

India

Out of Stock.

Omperazole Paste Syringe

1. Introduction

Overview of Omeprazole Paste Syringe

The Omeprazole Paste Syringe is a medication created to help horses manage acid-related issues effectively. It falls under the category of proton pump inhibitors (PPIs) commonly employed to decrease gastric acid production. This paste form provides a way to administer the medication accurately and for absorption, by the horses system.


Importance of Omeprazole in Gastrointestinal Health

The gastrointestinal system is intricately balanced, with stomach acid playing a crucial role in digestion. However, excessive acid production can lead to conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and gastritis. Omeprazole regulates acid secretion, promoting mucosal healing and preventing complications like esophageal damage.

Forms and Availability of Omeprazole Paste Syringe

  • Omeprazole is available in various formulations, including capsules, tablets, and suspensions.
  • The paste syringe format is particularly beneficial for individuals who have difficulty swallowing pills.
  • It is commonly used in both human and veterinary medicine, ensuring effective acid suppression in diverse patient groups.

2. Composition of Omeprazole Paste Syringe

Active Ingredients and Their Mechanism

Omeprazole is the ingredient in this product – a strong proton pump inhibitor that binds permanently to the enzyme system in gastric parietal cells responsible for pumping out acid. This process effectively stops production. Offers lasting relief for conditions related to excess stomach acidity.


Inactive Ingredients and Their Role

Omeprazole Paste Syringe contains excipients that enhance drug stability, bioavailability, and ease of administration. These may include:

  • Suspending agents to maintain uniform consistency.
  • Flavoring agents to improve palatability.
  • Buffers to optimize pH and stability.

How Omeprazole Paste Syringe Differs from Other Forms of Omeprazole

Compared to medications that come in pill form or liquid bottles with measuring cups, the paste syringe offers precise dosing control and makes it easier for patients to follow their prescribed regimen. This method is especially beneficial for children and animals in need of medication as it allows for administration tailored to their needs.

3. Uses of Omeprazole Paste Syringe

Approved Uses for Omeprazole Paste Syringe

Omeprazole paste syringe for horses is a medication used to treat and prevent gastric ulcers in horses. It is a proton pump inhibitor, which means that it works by reducing the amount of acid produced in the stomach. This can help to heal existing ulcers and prevent new ones from forming.

3.2 Off-Label Uses of Omeprazole Paste Syringe

Treatment of Acid-Related Disorders in Animals

Veterinary practices involve addressing ulcers and acid reflux in horses and small animals to enhance their well-being.

Use in Eosinophilic Esophagitis

Sometimes doctors recommend Omeprazole to treat a condition called eosinophilic esophagitis, which causes inflammation of the esophagus due to system issues.

4. How Omeprazole Paste Syringe Works

Mechanism of Action: Proton Pump Inhibition

The medication Omeprazole works by stopping the process in the production of stomach acid by blocking the H+/k+ ATPase enzyme activity, which results in a lasting reduction of acid levels in the stomach.

Effect on Stomach Acid Production

After being taken by a horse, omeprazole quickly decreases the production of stomach acid, leading to relief from symptoms and supporting the healing of the lining in the stomach.

Duration of Action and Absorption Rate

  • Onset of action: Within one hour.
  • Peak effect: Two to three hours post-administration.
  • Duration: Lasts up to 24 hours.

Differences Between Omeprazole and Other Proton Pump Inhibitors (PPIs)

When it comes to PPIs in the market today, omeprazole stands out for its proven safety record and versatility, making it a popular option for managing acid reflux.

5. Dosage and Administration

Omeprazole paste dosage for adult horses

Standard adult dosage ranges from 20mg to 40mg per day, depending on the condition being treated.

Adjusted Dosage for young horses

For young horses, the dosage of omeprazole paste syringe may need to be adjusted. It is important to talk to your veterinarian to determine the correct dosage for your young horse. Young horses are more susceptible to gastric ulcers than older horses, so it is important to take steps to prevent them.


Special Dosage Considerations for Elderly horses

Elderly patients may require changes to their medication doses because of changes in how their bodies process drugs and how well their kidneys function.

How to Administer Omeprazole Paste Syringe

Step-by-Step Guide to Proper Administration

  • Make sure the horse's mouth is clean and free of any food or debris.
  • Insert the syringe into the corner of the horse's mouth, aiming towards the back of the tongue.
  • Slowly depress the plunger until the entire dose has been delivered.
  • Allow the horse to swallow the paste.


6. Side Effects of Omeprazole Paste Syringe

Common Side Effects

Serious Side Effects

Allergic Reactions and Hypersensitivity

Severe allergic reactions, though rare, may include rash, swelling, and difficulty breathing.

7. Warnings and Precautions

Important Precautions Before Using Omeprazole Paste Syringe

  • Do not use in horses that are pregnant or lactating.
  • Do not use in horses with a history of hypersensitivity to omeprazole.
  • Do not use in horses with liver or kidney disease.
  • Use caution when using omeprazole paste syringe in horses with heart disease.


Contraindications

Hypersensitivity to Omeprazole or PPIs

Patients with a history of hypersensitivity reactions to omeprazole or other PPIs should avoid its use. Symptoms may include urticaria, anaphylaxis, or angioedema.

Careful Administration in Specific Populations

Use in Elderly Patients: Risks and Adjustments

Elderly individuals may need doses or longer intervals, between doses to avoid buildup of the drug due to changes in liver and kidney function, with age.

Use in Pregnant Women and Nursing Mothers

While omeprazole is classified as pregnancy category C, it should not be used on pregnant and lactating horses. 

Administration in Pediatric Patients

Younger horses tend to be more prone, to developing ulcers and may require medication so it's important to proceed with caution, in cases.  

8. Drug Interactions

Medications That May Affect Omeprazole Efficacy

Antacids and H2 Blockers

When antacids are taken together with omeprazole it might affect how omeprazole is absorbed into the body; however in cases this interaction doesn't have an impact, on health outcomes.

Antibiotics and Antifungal Medications

Medications such as clarithromycin and fluconazole are known to raise plasma levels by inhibiting CYP34 enzymes.

Medications That Omeprazole May Interact With

Blood Thinners (Warfarin, Clopidogrel)

Taking omeprazole might lower the effectiveness of clopidogrel in preventing blood clots from forming due to reduced activation levels in the body system; therefore, other proton pump inhibitors, like pantoprazole, are frequently chosen instead.

9. Overdosage and Emergency Management

Symptoms of Omeprazole Overdose

  • Loss of appetite
  • Vomiting
  • Diarrhea
  • Colic
  • Muscle weakness
  • Depression

Immediate Steps to Take in Case of Overdose

In the event of an overdose, seek medical attention immediately. Gastric lavage and supportive care may be required.

Treatment and Medical Intervention for Overdose Cases

There isn't an antidote for an overdose of omeprazole; the main approach to treatment revolves around providing relief for symptoms and offering care.

10. Handling, Storage, and Disposal

Proper Storage Conditions for Omeprazole Paste Syringe

Ideal Temperature and Humidity Conditions

Remember to store the paste in a dry spot, within temperatures ranging from 15°C to 30°C, and shield it from moisture and direct sunlight.

Protecting the Syringe from Light and Moisture

Exposure to light and moisture can break down the components. Lessen their effectiveness.

Safe Handling and Administration Precautions

Avoiding Contamination During Use

Remember to have hands when you're handling a syringe and avoid sharing them to steer clear of any contamination risks.

Ensuring Correct Dosing for Different Patients

Dosage levels must be precisely calculated to avoid under or overmedication risks, with attention to children and the elderly.

Disposal Guidelines for Used or Expired Syringes

Environmentally Safe Disposal Practices

Unused medication should be properly disposed of, in compliance with guidelines to avoid harming the environment.

Proper Waste Management for Medical Supplies

Make sure to dispose of used syringes, in the assigned medical waste bins to prevent any exposure incidents.

11. Conclusion

Summary of Key Takeaways

Omeprazole Paste Syringe is an effective treatment for acid-related disorders, offering precise dosing and rapid relief. It is widely used in both human and veterinary medicine.

When to Seek Medical Advice

  • Persistent symptoms despite treatment.
  • Signs of an allergic reaction.
  • Adverse effects affecting quality of life.

Omperazole Paste Syringe FAQ

How to administer omeprazole to a horse?

When giving omeprazole to a horse, make sure not to provide any food in its mouth; instead, gently place the syringe into the gap between the teeth in the horse's mouth to ensure that the medication reaches either the back of the tongue or inside the cheek pouch effectively.

Is there an injectable omeprazole?

Yes

How much human omeprazole to give a horse?

Begin the treatment of horses using a dosage of 2 mg/kg of omeprazole initially with the option to escalate the dosage to 4 mg/kg if necessary following a lack of response observed clinically or through gastroscopy conducted by a veterinarian for visualization of the stomach wall.

Is veterinary omeprazole the same as human omeprazole?

Omeprazole, for dogs, comes in the form of tablets and capsules, similar to those used by humans.

How to give omeprazole to horses?

The medication needs to be placed at the back of the horse's tongue or deep in its cheek pouch, ensuring that the horse swallows the dose properly and doesn't spit it out afterward during an observation period to confirm ingestion success.

What size needle for horse injection?

When dealing with solutions, like penicillin, it is advised to use a needle with an 18 gauge size; for thinner watery solutions, a smaller needle of 20 to 21 gauge is more suitable.

What is the biggest side effect of omeprazole?

It may also lead to stomach-related issues like nausea or vomiting and diarrhea.

What is more powerful than omeprazole?

Esomeprazole

Can omeprazole cause kidney damage?

Yes

What is a natural substitute for omeprazole?

Turmeric

How quickly does omeprazole work?

It usually takes about 2 to 3 days for omeprazole to begin showing effects; however, it might take up to 4 weeks for its full effectiveness to be evident.

How do you give a horse oral paste?

When giving the medication to your horse, gently move the syringe in and around the horse's mouth to prompt swallowing and ensure the paste spreads evenly on the back of its tongue. Make sure you avoid depositing a clump that could be spit out easily. Lift your horse's head slightly for a while to help him swallow the medication properly.

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