BENICAR HCT Benicar HCT (OLMESARTAN MEDOXOMIL-HYDROCHLOROTHIAZIDE) Manufactured by Sankyo Pharma is a combination of an angiotensin II receptor antagonist (AT1 subtype), olmesartan medoxomil, and a thiazide diuretic, hydrochlorothiazide (HCTZ). Benicar HCT is used to treat hypertension. What is angiotensin? Angiotensin is a hormone and is mainly of two types, angiotensin 1 and angiotensin 2. It is a potent vasoconstrictor, meaning it constricts blood vessels, increasing the blood pressure. This function is achieved by stimulating the Gq protein in smooth muscle cells of the blood vessels which in turn activates contraction by an IP3-dependent mechanism. It is synthesized from
A Magic Pill for Treating Impotency in Men Suffering From ED There have been many written as well as said facts about the wonder drug Viagra in treating male erectile dysfunction. Its benefits versus risk ratio has been tested from time to time by many medical studies. The statistics based upon those studies, prove its true nature. Media has reported many of its adverse reactions on patients taking Viagra, however, as long as the statistics prove its worth, this drug will continue to serve to its true value. Have a look at some of the facts related to its functioning
Sildenafil Citrate is a virility drug in the form of a white crystalline powder which men use to treat their inability to sustain an erection, known as impotence. When taken, for a temporary amount of time the drug normalizes the erectile function of the penis, hence an erection during intercourse can be achieved effectively. It does this by restraining a particular enzyme known as cGMP specific phosphodiesterase type 5. This enzyme is known to prevent and forbid the production of a chemical that causes erections. By taking sildenafil (in the form of a pill), for a temporary amount of time
Viagra: “Is It for You” INTRODUCTION Advancements in the field of science have a tremendous effect in the lifestyle of people around the world. The things which we were only conceiving in our minds a long time ago came into reality after years of research and testing of the greatest minds of every century. The pursuit for the elixir of life has become a race for most developed countries so a lot of them are investing a lot of money, time and effort just to bring quality life in every household around the globe, most especially to those who can
ACTONEL (risedronate sodium tablets), manufactured by Procter & Gamble Pharmaceuticals, Inc is a pyridinyl bisphosphonate that inhibits osteoclast-mediated bone resorption and modulates bone metabolism. It is mainly used in the prevention and treatment of osteoporosis in post menopausal women. Osteoporosis: It is a pathological condition which affects the bones by increasing their risk of fracture. In this condition, there is decrease in the Bone Mineral Density [BMD], which results in the alteration of the whole micro architecture of the bone. The World Health Organization [WHO] defines osteoporosis in women as a bone mineral density 2.5 standard deviations below
KAMAGRA (GENERIC VIAGRA) [sildenafil citrate], manufactured by Ajanta Pharma, Ltd, this drug is the first cyclic guanosine monophosphate [cGMP] specific phosphodiesterase type 5 enzyme inhibitor. This enzyme helps in regulating the blood circulation in the penile tissue. This leads to better penile erection. Kamagra (Generic Viagra) is primarily indicated in the treatment of impotence [erectile dysfunction] The compound sildenafil was synthesized in Pfizer’s research lab in Kent, England. Believe it or not, sildenafil was actually being studied for the treatment of hypertension and angina pectoris. Angina pectoris, or chest pain, caused by an insufficient supply of oxygen and
Acomplia (Rimonabant), marketed by Sanofi- Aventis is a selective CB1 endocannabinoid receptor antagonist indicated for the treatment of obesity. Its mechanism of action is to block the endogenous cannabinoid binding to neuronal CB1 receptors. What is endocannabinoid system? The endocannabinoid system is in the part of the brain that regulates metabolism, energy levels and appetite. With reference to the above drug, endocannabinoid receptors on activation will increase the appetite. Hence, drugs like Acomplia (Rimonabant) will block this endocannabinoid receptor, eventually leading to a decrease in the appetite. It is the most advanced endocannabinoid receptor antagonist in clinical development and offers
ACCUTANE Accutane [isotretinoin], marketed by Roche Laboratories, is used in the treatment of acne. Isotretinoin is an isomer of tretinoin. Accutane basically decreases the amount of sebum secreted by the sebaceous glands and helps prevent/cure acne. Acne vulgaris: What exactly is acne? Our skin especially, over the face has a structure called as the pilo-sebaceous unit [skin structures consisting of a hair follicle and its associated sebaceous gland]. It contains the hair follicle and the sebum gland along with its duct. Now, the function of sebum gland is to secrete sebum which then gets expressed on the skin
ZELNORM Zelnorm [tegaserod] marketed by Novartis, is a 5 HT4 receptor partial agonist that binds with a high affinity at human 5-HT4 receptors. By acting as an agonist at neuronal 5-HT receptors, it triggers the release of further neuro transmitters such as calcitonin gene-related peptide from sensory neurons. The activation of 5-HT4 receptors in the gastro intestinal tract stimulates the peristaltic reflux and intestinal secretions, as well as inhibits visceral sensitivity. INDICATIONS: - Short term treatment of irritable bowel syndrome [IBS] whole primary bowel symptoms is constipation, bloating, and abdominal pain. DOSAGE: 6 mg Zelnorm taken twice
VENTOLIN Ventolin Aerosol, [albuterol sulfate], marketed by Glaxo Wellcome Inc. is a pressurized metered-dose aerosol unit for oral inhalation. The base which is recommended by the World Health Organization is Salbutamol. Ventolin is indicated for the treatment or prevention of bronchospasm in adults and children 4 years of age and older with reversible obstructive airway disease and for the prevention of exercise-induced bronchospasm in patients 4 years of age and older. Ventolin is a short acting sympathomimetic (beta agonist) bronchodilator that relaxes the smooth muscle in the airways allowing effort free airflow in the lungs. It is chemically